Compounds > 1-[2-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-oxoethyl]pyrrolidine-2,5-dione
Page last updated: 2024-09-28

1-[2-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-oxoethyl]pyrrolidine-2,5-dione

Cross-References

ID SourceID
PubMed CID2113511
CHEMBL ID1404553
CHEBI ID92682
SCHEMBL ID17385567

Synonyms (30)

Synonym
HMS1753L14
smr000068650
MLS000057725 ,
ml031
SR-01000066488-3
1-[2-(1-benzyl-2,5-dimethylpyrrol-3-yl)-2-oxoethyl]pyrrolidine-2,5-dione
AKOS007958482
HMS2375P22
bdbm41648
1-[2-[2,5-dimethyl-1-(phenylmethyl)-3-pyrrolyl]-2-oxoethyl]pyrrolidine-2,5-dione
cid_2113511
1-[2-[2,5-dimethyl-1-(phenylmethyl)pyrrol-3-yl]-2-oxidanylidene-ethyl]pyrrolidine-2,5-dione
1-[2-(1-benzyl-2,5-dimethyl-pyrrol-3-yl)-2-keto-ethyl]pyrrolidine-2,5-quinone
852230-33-2
CHEMBL1404553
SCHEMBL17385567
CHEBI:92682
SR-01000066488-1
sr-01000066488
Z19746470
cym-5482
1-(2-(1-benzyl-2,5-dimethyl-1h-pyrrol-3-yl)-2-oxoethyl)pyrrolidine-2,5-dione
Q27164385
AS-16650
ml-031
CS-0034849
CJB23033
HY-111292
1-[2-(1-benzyl-2,5-dimethyl-1h-pyrrol-3-yl)-2-oxoethyl]pyrrolidine-2,5-dione
EN300-117401

Drug Classes (1)

ClassDescription
aromatic ketoneA ketone in which the carbonyl group is attached to an aromatic ring.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (14)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, Ferritin light chainEquus caballus (horse)Potency56.23415.623417.292931.6228AID485281
LuciferasePhotinus pyralis (common eastern firefly)Potency37.93300.007215.758889.3584AID588342
ATAD5 protein, partialHomo sapiens (human)Potency21.14460.004110.890331.5287AID504466; AID504467
TDP1 proteinHomo sapiens (human)Potency17.35820.000811.382244.6684AID686978; AID686979
thioredoxin glutathione reductaseSchistosoma mansoniPotency1.41250.100022.9075100.0000AID485364
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency7.07950.011212.4002100.0000AID1030
thyroid stimulating hormone receptorHomo sapiens (human)Potency19.95260.001318.074339.8107AID926; AID938
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency35.48130.035520.977089.1251AID504332
nuclear receptor ROR-gamma isoform 1Mus musculus (house mouse)Potency17.78280.00798.23321,122.0200AID2546
survival motor neuron protein isoform dHomo sapiens (human)Potency0.08910.125912.234435.4813AID1458
Guanine nucleotide-binding protein GHomo sapiens (human)Potency3.54811.995325.532750.1187AID624287
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
sphingosine 1-phosphate receptor 2Homo sapiens (human)EC50 (µMol)22.60101.20201.20201.2020AID872; AID874
Sphingosine 1-phosphate receptor 2Homo sapiens (human)EC50 (µMol)2.85300.00070.36512.8530AID854
Histamine H1 receptorCavia porcellus (domestic guinea pig)EC50 (µMol)1.20200.00260.53341.2020AID872
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (15)

Processvia Protein(s)Taxonomy
G protein-coupled receptor signaling pathwaySphingosine 1-phosphate receptor 2Homo sapiens (human)
sphingosine-1-phosphate receptor signaling pathwaySphingosine 1-phosphate receptor 2Homo sapiens (human)
positive regulation of cell population proliferationSphingosine 1-phosphate receptor 2Homo sapiens (human)
positive regulation of peptidyl-threonine phosphorylationSphingosine 1-phosphate receptor 2Homo sapiens (human)
actin cytoskeleton organizationSphingosine 1-phosphate receptor 2Homo sapiens (human)
filopodium assemblySphingosine 1-phosphate receptor 2Homo sapiens (human)
excitatory postsynaptic potentialSphingosine 1-phosphate receptor 2Homo sapiens (human)
negative regulation of excitatory postsynaptic potentialSphingosine 1-phosphate receptor 2Homo sapiens (human)
positive regulation of establishment of endothelial barrierSphingosine 1-phosphate receptor 2Homo sapiens (human)
regulation of metabolic processSphingosine 1-phosphate receptor 2Homo sapiens (human)
adenylate cyclase-activating G protein-coupled receptor signaling pathwaySphingosine 1-phosphate receptor 2Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulusGuanine nucleotide-binding protein GHomo sapiens (human)
renal water homeostasisGuanine nucleotide-binding protein GHomo sapiens (human)
G protein-coupled receptor signaling pathwayGuanine nucleotide-binding protein GHomo sapiens (human)
regulation of insulin secretionGuanine nucleotide-binding protein GHomo sapiens (human)
cellular response to glucagon stimulusGuanine nucleotide-binding protein GHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (9)

Processvia Protein(s)Taxonomy
G protein-coupled receptor bindingSphingosine 1-phosphate receptor 2Homo sapiens (human)
G protein-coupled receptor activitySphingosine 1-phosphate receptor 2Homo sapiens (human)
integrin bindingSphingosine 1-phosphate receptor 2Homo sapiens (human)
protein bindingSphingosine 1-phosphate receptor 2Homo sapiens (human)
lipid bindingSphingosine 1-phosphate receptor 2Homo sapiens (human)
G protein-coupled peptide receptor activitySphingosine 1-phosphate receptor 2Homo sapiens (human)
sphingosine-1-phosphate receptor activitySphingosine 1-phosphate receptor 2Homo sapiens (human)
G protein activityGuanine nucleotide-binding protein GHomo sapiens (human)
adenylate cyclase activator activityGuanine nucleotide-binding protein GHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (3)

Processvia Protein(s)Taxonomy
plasma membraneSphingosine 1-phosphate receptor 2Homo sapiens (human)
postsynapseSphingosine 1-phosphate receptor 2Homo sapiens (human)
plasma membraneSphingosine 1-phosphate receptor 2Homo sapiens (human)
cytoplasmSphingosine 1-phosphate receptor 2Homo sapiens (human)
plasma membraneGuanine nucleotide-binding protein GHomo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (15)

Assay IDTitleYearJournalArticle
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Current protocols in cytometry, Oct, Volume: Chapter 13Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2006Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set2010Assay and drug development technologies, Feb, Volume: 8, Issue:1
High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845Primary qHTS for Inhibitors of ATXN expression
AID504810Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID504812Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign2010Endocrinology, Jul, Volume: 151, Issue:7
A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's5 (71.43)24.3611
2020's1 (14.29)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
oxoamide[no description available]low00aromatic ketone
4-oxo-4-(3-pyridyl)butanoic acid[no description available]low00aromatic ketone;
monocarboxylic acid;
pyridines
bupropion[no description available]low00aromatic ketone;
monochlorobenzenes;
secondary amino compound		antidepressant;
environmental contaminant;
xenobiotic
bw 306u[no description available]low00aromatic ketone
kynurenine[no description available]low00aromatic ketone;
non-proteinogenic alpha-amino acid;
substituted aniline		human metabolite
monomethylpropion[no description available]low00aromatic ketone;
secondary amino compound
ro 48-8071[no description available]low00aromatic ether;
aromatic ketone;
bromobenzenes;
monofluorobenzenes;
olefinic compound;
tertiary amino compound		antineoplastic agent;
EC 5.4.99.7 (lanosterol synthase) inhibitor
amiodarone[no description available]low001-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
anisindione[no description available]low00aromatic ketone;
beta-diketone		anticoagulant;
vitamin K antagonist
acetovanillone[no description available]low00acetophenones;
aromatic ketone;
methyl ketone		antirheumatic drug;
EC 1.6.3.1. [NAD(P)H oxidase (H2O2-forming)] inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug;
plant metabolite
benzbromarone[no description available]low001-benzofurans;
aromatic ketone		uricosuric drug
bromperidol[no description available]low00aromatic ketone
buflomedil[no description available]low00aromatic ketone
celiprolol[no description available]low00aromatic ketone
droperidol[no description available]low00aromatic ketone;
benzimidazoles;
organofluorine compound		anaesthesia adjuvant;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic
dyclonine[no description available]low00aromatic ketone;
piperidines		topical anaesthetic
eperisone[no description available]low00aromatic ketone;
piperidines
eprazinone[no description available]low00aromatic ketone;
ether;
N-alkylpiperazine		mucolytic
ethacrynic acid[no description available]low00aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid		EC 2.5.1.18 (glutathione transferase) inhibitor;
ion transport inhibitor;
loop diuretic
haloperidol[no description available]low00aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol		antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
ketanserin[no description available]low00aromatic ketone;
organofluorine compound;
piperidines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
ketorolac[no description available]low00amino acid;
aromatic ketone;
monocarboxylic acid;
pyrrolizines;
racemate		analgesic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
non-steroidal anti-inflammatory drug
lofepramine[no description available]low00aromatic ketone;
dibenzoazepine;
monochlorobenzenes;
tertiary amino compound		antidepressant
mebendazole[no description available]low00aromatic ketone;
benzimidazoles;
carbamate ester		antinematodal drug;
microtubule-destabilising agent;
tubulin modulator
nocodazole[no description available]low00aromatic ketone;
benzimidazoles;
carbamate ester;
thiophenes		antimitotic;
antineoplastic agent;
microtubule-destabilising agent;
tubulin modulator
metyrapone[no description available]low00aromatic ketoneantimetabolite;
diagnostic agent;
EC 1.14.15.4 (steroid 11beta-monooxygenase) inhibitor
moperone[no description available]low00aromatic ketone
phenindione[no description available]low00aromatic ketone;
beta-diketone		anticoagulant
pifithrin[no description available]low00aromatic ketone
pipamperone[no description available]low00aromatic ketone;
bipiperidines;
monocarboxylic acid amide;
organofluorine compound;
tertiary amino compound		dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist
pirenperone[no description available]low00aromatic ketone
propafenone[no description available]low00aromatic ketone;
secondary alcohol;
secondary amino compound		anti-arrhythmia drug
propiomazine[no description available]low00aromatic ketone;
phenothiazines;
tertiary amino compound		dopaminergic antagonist;
histamine antagonist;
muscarinic antagonist;
phenothiazine antipsychotic drug;
sedative;
serotonergic antagonist
raloxifene[no description available]low001-benzothiophenes;
aromatic ketone;
N-oxyethylpiperidine;
phenols		bone density conservation agent;
estrogen antagonist;
estrogen receptor modulator
spiperone[no description available]low00aromatic ketone;
azaspiro compound;
organofluorine compound;
piperidines;
tertiary amino compound		alpha-adrenergic antagonist;
antipsychotic agent;
dopaminergic antagonist;
psychotropic drug;
serotonergic antagonist
suprofen[no description available]low00aromatic ketone;
monocarboxylic acid;
thiophenes		antirheumatic drug;
drug allergen;
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
peripheral nervous system drug
tiaprofenic acid[no description available]low00aromatic ketone;
monocarboxylic acid;
thiophenes		drug allergen;
non-steroidal anti-inflammatory drug
tolmetin[no description available]low00aromatic ketone;
monocarboxylic acid;
pyrroles		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor;
non-steroidal anti-inflammatory drug
tolperisone[no description available]low00aromatic ketone
trifluperidol[no description available]low00aromatic ketone
zomepirac[no description available]low00aromatic ketone;
monocarboxylic acid;
monochlorobenzenes;
pyrroles		cardiovascular drug;
non-steroidal anti-inflammatory drug
acepromazine[no description available]low00aromatic ketone;
methyl ketone;
phenothiazines;
tertiary amino compound		phenothiazine antipsychotic drug
benziodarone[no description available]low00aromatic ketone
musk ketone[no description available]low00aromatic ketone
quinophthalone[no description available]low00aromatic ketone;
beta-diketone;
quinolines		dye
2-acetylthiophene[no description available]low00aromatic ketone
diethylpropion[no description available]low00aromatic ketone;
tertiary amine		appetite depressant
adrenalone[no description available]low00aromatic ketone
dibenzoylmethane[no description available]low00aromatic ketone;
beta-diketone		antimutagen;
antineoplastic agent;
metabolite
pyrazolanthrone[no description available]low00anthrapyrazole;
aromatic ketone;
cyclic ketone		antineoplastic agent;
c-Jun N-terminal kinase inhibitor;
geroprotector
benzil[no description available]low00alpha-diketone;
aromatic ketone
4'-(chloroacetyl)acetanilide[no description available]low00acetamides;
alpha-chloroketone;
aromatic ketone
3-acetylpyridine[no description available]low00aromatic ketone
ninhydrin[no description available]low00aromatic ketone;
beta-diketone;
indanones;
ketone hydrate		colour indicator;
human metabolite
capillin[no description available]low00aromatic ketone;
ynone
gallacetophenone[no description available]low00aromatic ketone
1-phenyl-1,2-propanedione[no description available]low00alpha-diketone;
aromatic ketone		plant metabolite
1,3-indandione[no description available]low00aromatic ketone;
beta-diketone;
indanones
phenacylamine[no description available]low00aromatic ketone
2-acetylpyrrole[no description available]low00aromatic ketone;
methyl ketone;
pyrroles
2-acetylpyridine[no description available]low00aromatic ketone
pyrovalerone[no description available]low00aromatic ketone
2-acetylfuran[no description available]low00aromatic ketone;
furans;
methyl ketone
sapropterin[no description available]low00aromatic ketone
fluanisone[no description available]low00aromatic ketone
3-Acetyl-2,4-dimethylpyrrole[no description available]low00aromatic ketone
metylperon[no description available]low00aromatic ketone
azaperone[no description available]low00aminopyridine;
aromatic ketone;
monofluorobenzenes;
N-alkylpiperazine;
N-arylpiperazine;
tertiary amino compound		antipsychotic agent;
dopaminergic antagonist
Propioveratrone[no description available]low00aromatic ketone
benperidol[no description available]low00aromatic ketone
2,4-diacetylphloroglucinol[no description available]low00aromatic ketone;
benzenetriol;
diketone;
methyl ketone		antifungal agent;
bacterial metabolite
4-benzoylpyridine[no description available]low00aromatic ketone
pyoluteorin[no description available]low00aromatic ketone;
beta-hydroxy ketone;
diol;
organochlorine compound;
organochlorine pesticide;
polyketide;
pyrroles;
resorcinols		antibacterial agent;
antifungal agent;
apoptosis inducer;
bacterial metabolite;
marine metabolite
flubendazole[no description available]low00aromatic ketone;
benzimidazoles;
carbamate ester;
organofluorine compound		antinematodal drug;
teratogenic agent
4-ipomeanol[no description available]low00aromatic ketone
ticrynafen[no description available]low00aromatic ether;
aromatic ketone;
dichlorobenzene;
monocarboxylic acid;
thiophenes		antihypertensive agent;
hepatotoxic agent;
loop diuretic
celiprolol hydrochloride[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-(1-imidazolyl)ethanone[no description available]low00aromatic ketone
enoximone[no description available]low00aromatic ketone
bupropion hydrochloride[no description available]low00aromatic ketone
3-oxo-3-phenylpropanenitrile[no description available]low00aromatic ketone;
beta-ketonitrile
fenofibric acid[no description available]low00aromatic ketone;
chlorobenzophenone;
monocarboxylic acid		drug metabolite;
marine xenobiotic metabolite
inaperisone[no description available]low00aromatic ketone
valerophenone[no description available]low00aromatic ketoneplant metabolite;
volatile oil component
2,4,6-trihydroxyacetophenone[no description available]low00aromatic ketone;
benzenetriol;
methyl ketone		MALDI matrix material;
plant metabolite
perilla ketone[no description available]low00aromatic ketone
butofilolol[no description available]low00aromatic ketone
2,6-dihydroxyacetophenone[no description available]low00aromatic ketone
2',4'-Dimethoxypropiophenone[no description available]low00aromatic ketone
propipocaine[no description available]low00aromatic ketone
hp 873[no description available]low001,2-benzoxazoles;
aromatic ether;
aromatic ketone;
methyl ketone;
monoamine;
organofluorine compound;
piperidines;
tertiary amino compound		dopaminergic antagonist;
second generation antipsychotic;
serotonergic antagonist
prifelone[no description available]low00aromatic ketone
metamfepramone[no description available]low00aromatic ketone
1-(2,4-dihydroxyphenyl)-1-hexanone[no description available]low00aromatic ketone
1-(2,4-Dihydroxyphenyl)-1-butanone[no description available]low00aromatic ketone
isoxaflutole[no description available]low00(trifluoromethyl)benzenes;
aromatic ketone;
cyclopropanes;
isoxazoles;
sulfone		agrochemical;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
proherbicide
sulcotrione[no description available]low00aromatic ketone;
beta-triketone;
cyclohexanones;
sulfone		carotenoid biosynthesis inhibitor;
environmental contaminant;
herbicide;
xenobiotic
tolperisone hydrochloride[no description available]low00aromatic ketone
beta-(4-fluorobenzoyl)propionic acid[no description available]low00aromatic ketone
lobeline[no description available]low00aromatic ketone;
piperidine alkaloid;
tertiary amine		nicotinic acetylcholine receptor agonist
aflatoxin q1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human xenobiotic metabolite
desethylamiodarone[no description available]low00aromatic ketone
ly 117018[no description available]low001-benzothiophenes;
aromatic ketone;
N-alkylpyrrolidine;
phenols		bone density conservation agent;
estrogen receptor antagonist;
estrogen receptor modulator
fpl 55712[no description available]low00aromatic ketone
(6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide[no description available]low00aromatic ketone
4-hydoxy-1-(3-pyridyl)-1-butanone[no description available]low00aromatic ketone
1-[4-[2-hydroxy-3-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]propoxy]phenyl]-1-propanone[no description available]low00aromatic ketone
3-(1-piperidinyl)-1-(4-propan-2-yloxyphenyl)-1-propanone[no description available]low00aromatic ketone
3-n-methylspiperone[no description available]low00aromatic ketone
ly 255283[no description available]low00aromatic ketone
eperisone[no description available]low00aromatic ketone
n-(4-aminophenethyl)spiroperidol[no description available]low00aromatic ketone
esonarimod[no description available]low00aromatic ketone
oxoline[no description available]low00aromatic ketone;
tetralins		geroprotector
n-acetyl-n-formyl-5-methoxykynurenamine[no description available]low00aromatic ketone
4(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridine[no description available]low00aromatic ketone
mesotrione[no description available]low00aromatic ketone;
beta-triketone;
C-nitro compound;
sulfone		carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
environmental contaminant;
herbicide;
xenobiotic
rs 67333[no description available]low00aromatic ketone
aflatoxin b1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone		carcinogenic agent;
human metabolite
dronedarone[no description available]low001-benzofurans;
aromatic ether;
aromatic ketone;
sulfonamide;
tertiary amino compound		anti-arrhythmia drug;
environmental contaminant;
xenobiotic
alpha-pyrrolidinopropiophenone[no description available]low00aromatic ketone
(1-tert-butyl-5-phenyl-3-pyrrolyl)-phenylmethanone[no description available]low00aromatic ketone
veratrone[no description available]low00aromatic ketone;
dimethoxybenzene;
primary alcohol
7-benzoyl-3-chloroindolizine-1,2-dicarboxylic acid dimethyl ester[no description available]low00aromatic ketone
bromodeoxytopsentin[no description available]low00aromatic ketone;
bromoindole;
imidazoles;
indole alkaloid		antibacterial agent;
EC 2.7.1.40 (pyruvate kinase) inhibitor;
marine metabolite
amiodarone hydrochloride[no description available]low00aromatic ketone
knipholone[no description available]low00aromatic ketone;
dihydroxyanthraquinone;
methoxybenzenes;
methyl ketone;
polyphenol;
resorcinols		antineoplastic agent;
antioxidant;
antiplasmodial drug;
leukotriene antagonist;
metabolite
alpha bitter acid[no description available]low00aromatic ketone;
cyclic ketone;
diketone;
tertiary alpha-hydroxy ketone;
triol		antibacterial drug;
antioxidant;
cyclooxygenase 2 inhibitor;
metabolite
2-Acetylthiazole[no description available]low00aromatic ketone
1-[3-acetyl-5-[(4-bromophenyl)-oxomethyl]-1,3,7-triazabicyclo[3.3.1]nonan-7-yl]ethanone[no description available]low00aromatic ketone
LSM-42773[no description available]low00aromatic ketone
1-(4-methylphenyl)-2-(1H-1,2,4-triazol-5-ylthio)ethanone[no description available]low00aromatic ketone
3-(4-fluoroanilino)-1-(3-nitrophenyl)-1-propanone[no description available]low00aromatic ketone
(5-methoxy-3-benzofuranyl)-phenylmethanone[no description available]low00aromatic ketone
3-Hydroxy-1-(4-hydroxyphenyl)-1-propanone[no description available]low00aromatic ketone
(2-amino-5-methyl-3-thiophenyl)-thiophen-2-ylmethanone[no description available]low00aromatic ketone;
thiophenes
1-(2,5-dimethoxyphenyl)-2-[[5-(2-furanyl)-4-propyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(1,3-benzodioxol-5-ylmethyl)-3-hydroxy-3-[2-(4-methylphenyl)-2-oxoethyl]-2-indolone[no description available]low00aromatic ketone
2-[(5-amino-1-phenacyl-1,2,4-triazol-3-yl)thio]-N-(3-cyano-4,5-dimethyl-2-thiophenyl)acetamide[no description available]low00aromatic ketone
2-[[1-(2-methoxyethyl)-5-tetrazolyl]thio]-1-phenylethanone[no description available]low00aromatic ketone
1-(4-methoxyphenyl)-2-(5-thiophen-2-yl-2-tetrazolyl)ethanone[no description available]low00aromatic ketone
1-(3-methoxyphenyl)-2-[[4-methyl-5-[[(4-phenyl-2-thiazolyl)amino]methyl]-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(5-chloro-2-methoxyphenyl)-2-[(4,6-diamino-2-pyrimidinyl)thio]ethanone[no description available]low00aromatic ketone
2-[(5-methyl-1H-1,2,4-triazol-3-yl)thio]-1-phenylethanone[no description available]low00aromatic ketone
1-(4-chlorophenyl)-2-[[4-ethyl-5-(2-methyl-3-furanyl)-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(3,4-dichlorophenyl)-2-[[4-(2-furanylmethyl)-5-(3-pyridinyl)-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
(4-chloro-5-hydroxy-3-benzofuranyl)-phenylmethanone[no description available]low00aromatic ketone
3-(3-benzoyl-6-chloro-4,5-dihydroxy-7-benzofuranyl)pentane-2,4-dione[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(2-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(4-fluorophenyl)-2-[[4-(2-furanylmethyl)-5-(phenoxymethyl)-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-thiophen-2-ylacetamide[no description available]low00aromatic ketone
4-thiomorpholinecarbodithioic acid [2-(4-chlorophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
1-[4-[(2-methyl-4-quinolinyl)amino]phenyl]ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[(4,6-dimethyl-2-pyrimidinyl)thio]ethanone[no description available]low00aromatic ketone
1-(4-Chlorophenyl)-2-[(1-methyl-1H-imidazol-2-yl)thio]ethan-1-one[no description available]low00aromatic ketone
4-(4-ethoxyphenyl)-4-oxobutanoic acid[no description available]low00aromatic ketone
4-bromo-N-phenacylbenzamide[no description available]low00aromatic ketone
N1-[2-(4-chlorophenyl)-2-oxoethyl]-4-chlorobenzamide[no description available]low00aromatic ketone
1-[4-[(4,6-dimethyl-2-pyrimidinyl)amino]phenyl]ethanone[no description available]low00aromatic ketone
4-amino-2-(phenacylthio)-5-pyrimidinecarboxylic acid ethyl ester[no description available]low00aromatic ketone
(3-hydroxy-5,6,7,8-tetrahydro-4H-cyclohepta[d]imidazol-2-yl)-phenylmethanone[no description available]low00aromatic ketone
2-fluoro-N-phenacylbenzamide[no description available]low00aromatic ketone
2-(Benzotriazol-1-yl)-1-(4-bromophenyl)ethanone[no description available]low00aromatic ketoneanticoronaviral agent
2-(4-methylanilino)-1-(4-nitrophenyl)ethanone[no description available]low00aromatic ketone
1-(3-((2',4'-Dimethyl-[4,5'-bithiazol]-2-yl)amino)phenyl)ethanone[no description available]low00aromatic ketone
1-[4-(1-azepanyl)-3-fluorophenyl]-1-propanone[no description available]low00aromatic ketone
2-(8-quinolinylthio)acetic acid phenacyl ester[no description available]low00aromatic ketone
2-(4-ethoxyanilino)-1-(4-methylphenyl)ethanone[no description available]low00aromatic ketone
1-[4-[[6-methyl-2-(methylthio)-5-prop-2-enyl-4-pyrimidinyl]amino]phenyl]ethanone[no description available]low00aromatic ketone
(4-methoxyphenyl)-(3-methyl-2-propyl-4-imidazolyl)methanone[no description available]low00aromatic ketone
5-[(5-acetyl-2-propan-2-yloxyphenyl)methyl]-6-hydroxy-2-sulfanylidene-1H-pyrimidin-4-one[no description available]low00aromatic ketone
N-(5-benzoyl-4-phenyl-2-thiazolyl)carbamic acid methyl ester[no description available]low00aromatic ketone
2-chloro-N-[5-ethyl-3-[(4-methylphenyl)-oxomethyl]-2-thiophenyl]acetamide[no description available]low00aromatic ketone
1-(4-fluorophenyl)-2-(2-pyridinylthio)ethanone[no description available]low00aromatic ketone
N-(3-acetylphenyl)-2-thiophen-2-ylacetamide[no description available]low00aromatic ketone
3-(4-bromoanilino)-1-(3-nitrophenyl)-1-propanone[no description available]low00aromatic ketone
3-anilino-1-(3-nitrophenyl)-1-propanone[no description available]low00aromatic ketone
1-(5-ethyl-2,4-dihydroxyphenyl)-2-(2-fluorophenoxy)ethanone[no description available]low00aromatic ketone
3-[1-(4-acetylphenyl)-5-thiophen-2-yl-2-pyrrolyl]propanoic acid[no description available]low00aromatic ketone
(7-methoxy-2-benzofuranyl)-(4-nitrophenyl)methanone[no description available]low00aromatic ketone
4-[2-(3-methoxyphenyl)-2-oxoethoxy]benzoic acid methyl ester[no description available]low00aromatic ketone
4-phenacyloxybenzoic acid methyl ester[no description available]low00aromatic ketone
1-(2-hydroxyphenyl)-2-(2H-tetrazol-5-yl)ethanone[no description available]low00aromatic ketone
2-(methylamino)benzoic acid [2-(4-fluorophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-[(4-methyl-2-pyrimidinyl)thio]-1-(3-nitrophenyl)ethanone[no description available]low00aromatic ketone
3-[[(3-acetylanilino)-oxomethyl]amino]-2-thiophenecarboxylic acid methyl ester[no description available]low00aromatic ketone
1-(3-acetylphenyl)-3-(2-pyridinylmethyl)urea[no description available]low00aromatic ketone
1-(4-acetylphenyl)-3-[2-(4-fluorophenyl)ethyl]thiourea[no description available]low00aromatic ketone
1-phenyl-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)ethanone[no description available]low00aromatic ketone
3-tert-butyl-7-[[2-(4-methylphenyl)-2-oxoethyl]thio]-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one[no description available]low00aromatic ketone
LSM-4563[no description available]low00aromatic ketone
1-[4-[3-[5-(2-furanyl)-1H-pyrazol-3-yl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]phenyl]ethanone[no description available]low00aromatic ketone
1,3-diphenyl-4-pyrazolecarboxylic acid [2-(4-methyl-3-nitrophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
Silica aerogel[no description available]low00aromatic ketone
2-[[5-(1-benzotriazolylmethyl)-4-methyl-1,2,4-triazol-3-yl]thio]-1-(2-fluorophenyl)ethanone[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-[[1-(3,5-dimethoxyphenyl)-5-tetrazolyl]thio]acetamide[no description available]low00aromatic ketone
3,4-dimethoxybenzoic acid [2-(3,4-dimethoxyphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-[2-[2-(4-chlorophenyl)-2-oxoethoxy]phenyl]isoindole-1,3-dione[no description available]low00aromatic ketone
2-[[5-(7-methoxy-2-benzofuranyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-1-(4-methoxyphenyl)ethanone[no description available]low00aromatic ketone
2-[[4,6-bis(1-piperidinyl)-1,3,5-triazin-2-yl]thio]-1-phenylethanone[no description available]low00aromatic ketone
1-(2,5-dimethylphenyl)-2-[(5-methyl-1,3,4-thiadiazol-2-yl)thio]ethanone[no description available]low00aromatic ketone
3-methyl-1,5-dithiophen-2-ylpentane-1,5-dione[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(4-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
2-[[5-(3-chlorophenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(3-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(4-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[[5-(3-methoxyphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]thio]ethanone[no description available]low00aromatic ketone
(4-chlorophenyl)-(5-hydroxy-2-methyl-4,6-dinitro-3-benzofuranyl)methanone[no description available]low00aromatic ketone
1-(3,4-dimethylphenyl)-2-[[5-[[2-(4-ethoxyanilino)-4-thiazolyl]methyl]-1,3,4-oxadiazol-2-yl]thio]ethanone[no description available]low00aromatic ketone
1-(4-fluorophenyl)-2-[(2-propyl-4-quinazolinyl)thio]ethanone[no description available]low00aromatic ketone
(5-chloro-2-hydroxyphenyl)-[2-ethyl-3-(4-fluorophenyl)-6-pyrazolo[1,5-a]pyrimidinyl]methanone[no description available]low00aromatic ketone
N,N-dimethylcarbamothioic acid O-[4-[2-[(4-chlorophenyl)thio]-1-oxoethyl]-2,6-dimethylphenyl] ester[no description available]low00aromatic ketone
4-[(4-tert-butylphenyl)-oxomethyl]-N-[2-(2-pyridinyl)ethyl]-1H-pyrrole-2-carboxamide[no description available]low00aromatic ketone
(4-chlorophenyl)-[5-(4-morpholinyl)-4-(2-pyridinyl)-2-thiophenyl]methanone[no description available]low00aromatic ketone
N,N-dimethylcarbamic acid [4-[2-(benzenesulfonyl)-1-oxoethyl]-2,6-dimethylphenyl] ester[no description available]low00aromatic ketone
N,N-dimethylcarbamic acid [4-[2-(4-fluorophenyl)sulfonyl-1-oxoethyl]-2,6-dimethylphenyl] ester[no description available]low00aromatic ketone
2-chloro-1-[1-(2-furanylmethyl)-2,5-dimethyl-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
N-[(phenacylamino)-sulfanylidenemethyl]-2-furancarboxamide[no description available]low00aromatic ketone
3-phenylpropionylglycine[no description available]low00aromatic ketone
4-amino-5-[(4-methylphenyl)-oxomethyl]-2-(prop-2-enylamino)-3-thiophenecarbonitrile[no description available]low00aromatic ketone
2-amino-4-[[2-(4-bromophenyl)-2-oxoethyl]thio]-3-azaspiro[5.5]undeca-1,4-diene-1,5-dicarbonitrile[no description available]low00aromatic ketone
2-[[4-ethyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]-1-(4-methylphenyl)ethanone[no description available]low00aromatic ketone
7-amino-9-(phenacylthio)-8-azaspiro[4.5]deca-6,9-diene-6,10-dicarbonitrile[no description available]low00aromatic ketone
6-(bromomethyl)-1,3-dimethyl-5-[(4-nitrophenyl)-oxomethyl]pyrimidine-2,4-dione[no description available]low00aromatic ketone
1-(2,4-dimethylphenyl)-2-([1,2,4]triazolo[4,3-a]pyridin-3-ylthio)ethanone[no description available]low00aromatic ketone
4-(4-acetylphenoxy)butanoic acid [5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]methyl ester[no description available]low00aromatic ketone
2-[[5-[(1,3-benzothiazol-2-ylthio)methyl]-4-ethyl-1,2,4-triazol-3-yl]thio]-1-(3,4-dihydroxyphenyl)ethanone[no description available]low00aromatic ketone
2-chloro-1-[2,5-dimethyl-1-(5-methyl-3-isoxazolyl)-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
2-[2-[[5-cyano-1-(3-methoxypropyl)-6-oxo-3-pyridinyl]-oxomethyl]-4-methoxyphenoxy]-N-(5-methyl-3-isoxazolyl)acetamide[no description available]low00aromatic ketone
3,5-dimethyl-4-isoxazolecarboxylic acid [2-(4-amino-1-methyl-2,6-dioxo-3-propyl-5-pyrimidinyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-[3-[(4-chlorophenyl)-oxomethyl]-6-methoxy-4-oxo-1-quinolinyl]-N-(4-fluorophenyl)acetamide[no description available]low00aromatic ketone;
quinolines
1-[4-[(2-amino-5-thiazolyl)methyl]phenyl]ethanone[no description available]low00aromatic ketone
[9-(4-ethoxyphenyl)sulfonyl-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone[no description available]low00aromatic ketone;
quinolines
4-chloro-N-[(phenacylamino)-sulfanylidenemethyl]benzamide[no description available]low00aromatic ketone
N-[(phenacylamino)-sulfanylidenemethyl]cyclohexanecarboxamide[no description available]low00aromatic ketone
4-(4-chlorophenyl)-4-oxobutanoic acid [2-(2-furanylmethylamino)-2-oxoethyl] ester[no description available]low00aromatic ketone
1-(2-chlorophenyl)-2-(3,5-dimethyl-4-nitro-1-pyrazolyl)ethanone[no description available]low00aromatic ketone
[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]-[4-(1-piperidinylsulfonyl)phenyl]methanone[no description available]low00aromatic ketone
4-(dimethylamino)benzoic acid [2-(2-methoxyphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-chloro-3-pyridinecarboxylic acid [2-(4-fluorophenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
3-(1,3-benzothiazol-2-yl)propanoic acid phenacyl ester[no description available]low00aromatic ketone
5-[(2-hydroxy-5-methylphenyl)-oxomethyl]-N,1-bis[2-(4-methoxyphenyl)ethyl]-2-oxo-3-pyridinecarboxamide[no description available]low00aromatic ketone
2-[(1-oxido-2-pyridin-1-iumyl)thio]-1-(4-phenylphenyl)ethanone[no description available]low00aromatic ketone
2-(1H-benzimidazol-2-yl)-1-(3-nitrophenyl)ethanone[no description available]low00aromatic ketone
2-[[2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl]thio]-3-pyridinecarboxylic acid[no description available]low00aromatic ketone
2-[[5-(2-furanyl)-1,3,4-oxadiazol-2-yl]thio]-1-(2-methoxyphenyl)ethanone[no description available]low00aromatic ketone
2-chloro-1-[1-[2-(4-chlorophenyl)ethyl]-2,5-dimethyl-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
2-chloro-3-pyridinecarboxylic acid [2-(4-ethylphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
3-(4-acetylphenyl)-1-(phenylmethyl)-1-propylthiourea[no description available]low00aromatic ketone
2-anilinobenzoic acid [2-(4-acetylanilino)-2-oxoethyl] ester[no description available]low00aromatic ketone
N-(2-acetylphenyl)-2-(2-oxo-1-quinoxalinyl)acetamide[no description available]low00aromatic ketone
2-[[5-(5-bromo-2-furanyl)-4-(phenylmethyl)-1,2,4-triazol-3-yl]thio]-1-(2-fluorophenyl)ethanone[no description available]low00aromatic ketone
4,5-dichloro-2-[2-[2,5-dimethyl-1-(2,2,2-trifluoroethyl)-3-pyrrolyl]-2-oxoethyl]-3-pyridazinone[no description available]low00aromatic ketone
7-[(4-acetylphenoxy)methyl]-5-thiazolo[3,2-a]pyrimidinone[no description available]low00aromatic ketone
(3-amino-4,6-dimethyl-2-thieno[2,3-b]pyridinyl)-(2-chlorophenyl)methanone[no description available]low00aromatic ketone
1-[4-[(2-bromophenyl)-oxomethyl]-1H-pyrrol-2-yl]-2,2,2-trichloroethanone[no description available]low00aromatic ketone
2-(4-hydroxy-1,3-thiazol-2-yl)-1-phenylethan-1-one[no description available]low00aromatic ketone
N-[1-(4-methyl-6-oxo-1-pyrimidinyl)-2-oxo-2-phenylethyl]benzamide[no description available]low00aromatic ketone
N-[5-ethyl-3-[(4-methoxyphenyl)-oxomethyl]-2-thiophenyl]-2-(4-methyl-1-piperazinyl)acetamide[no description available]low00aromatic ketone
4-[[5-ethyl-3-[(4-methoxyphenyl)-oxomethyl]-2-thiophenyl]amino]-4-oxobutanoic acid[no description available]low00aromatic ketone
(2-anilino-4-methyl-1,3-thiazol-5-yl)(4-methoxyphenyl)methanone[no description available]low00aromatic ketone
(4-chlorophenyl)-[6,7-dichloro-4-[(dimethylamino)methyl]-5-hydroxy-2-methyl-3-benzofuranyl]methanone[no description available]low00aromatic ketone
cid 2858522[no description available]low00aromatic ketone
1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-5-ylthio)ethanone[no description available]low00aromatic ketone
2-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]-1-phenylethanone[no description available]low00aromatic ketone
(3-amino-5-nitro-2-benzofuranyl)-phenylmethanone[no description available]low00aromatic ketone
2-nitrobenzoic acid [1-(4-methylphenyl)-1-oxopropan-2-yl] ester[no description available]low00aromatic ketone
3-hydroxy-3-[2-oxo-2-[4-(1-pyrrolyl)phenyl]ethyl]-1H-indol-2-one[no description available]low00aromatic ketone
1-[4-[3-[4-(4-fluorophenyl)-1-piperazinyl]-2-hydroxypropoxy]phenyl]-1-propanone[no description available]low00aromatic ketone
1-[4-[4-[[6-bromo-2-(3-pyridinyl)-4-quinolinyl]-oxomethyl]-1-piperazinyl]phenyl]ethanone[no description available]low00aromatic ketone
N-[4-[(3-acetylphenyl)sulfamoyl]phenyl]-1-piperidinecarboxamide[no description available]low00aromatic ketone
(2,5-dimethylphenyl)-(6-methyl-5-imidazo[2,1-b]thiazolyl)methanone[no description available]low00aromatic ketone
3-hydroxy-1-adamantanecarboxylic acid [2-[1-(2-methoxyethyl)-2,5-dimethyl-3-pyrrolyl]-2-oxoethyl] ester[no description available]low00aromatic ketone
[2-[(2,6-dimethyl-4-morpholinyl)-oxomethyl]phenyl]-(1H-imidazol-2-yl)methanone[no description available]low00aromatic ketone
3-(2-furanyl)-3-oxo-2-(2-pyridinyl)propanenitrile[no description available]low00aromatic ketone
1-[4-ethoxy-3-[[[4-(2-oxolanylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]thio]methyl]phenyl]ethanone[no description available]low00aromatic ketone
timiperone[no description available]low00aromatic ketone
adefovir[no description available]low00aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
organooxygen heterocyclic antibiotic;
polyphenol		antimalarial;
Aspergillus metabolite;
marine metabolite
phenyl-(2-thiophen-2-yl-5,10b-dihydro-1H-pyrazolo[1,5-c][1,3]benzoxazin-5-yl)methanone[no description available]low00aromatic ketone
N-[3-[(4-chlorophenyl)-oxomethyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-3-pyridinecarboxamide[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-[(4-methyl-1,2,4-triazol-3-yl)thio]ethanone[no description available]low00aromatic ketone
2-quinolinecarboxylic acid (1-oxo-1-phenylpropan-2-yl) ester[no description available]low00aromatic ketone
N-(3-acetylphenyl)-3-(1-ethyl-3-methyl-4-pyrazolyl)-4,5-dihydroisoxazole-5-carboxamide[no description available]low00aromatic ketone
1-[4-[4-[[1-(4-chlorophenyl)sulfonylcyclopropyl]-oxomethyl]-1-piperazinyl]phenyl]ethanone[no description available]low00aromatic ketone
1-[2-(4-bromophenyl)-2-oxoethyl]-3-(2-furanylmethyl)-6,7-dimethoxyquinazoline-2,4-dione[no description available]low00aromatic ketone
N-(3-acetylphenyl)-3,5-dimethyl-4-isoxazolesulfonamide[no description available]low00aromatic ketone
3-[4-[2-(3,4-dimethoxyphenyl)-2-oxoethyl]-3-oxo-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid[no description available]low00aromatic ketone
3-[(3-fluorophenyl)methyl]-8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one[no description available]low00aromatic ketone
4-[(4-acetyl-2-methoxyphenyl)methoxy]-3-methoxybenzoic acid [1-(carbamoylamino)-1-oxopropan-2-yl] ester[no description available]low00aromatic ketone
N-(2-chloro-3-pyridinyl)-3-oxo-3-phenylpropanamide[no description available]low00aromatic ketone
5-[2-(4-bromophenyl)-2-oxoethyl]-1,3-diphenyl-2-sulfanylidene-4-imidazolidinone[no description available]low00aromatic ketone
2-(thiophen-2-ylsulfonylamino)benzoic acid [2-(3-acetylanilino)-2-oxo-1-phenylethyl] ester[no description available]low00aromatic ketone
4-(4-chlorophenyl)-N-[3-[(4-methoxyphenyl)sulfamoyl]phenyl]-4-oxobutanamide[no description available]low00aromatic ketone
2-[4-[oxo(thiophen-2-yl)methyl]phenyl]propanoic acid methyl ester[no description available]low00aromatic ketone
N-[3-[(3-chlorophenyl)sulfamoyl]-4-methylphenyl]-3-(4-nitrophenyl)-3-oxopropanamide[no description available]low00aromatic ketone
rs 102221[no description available]low00aromatic ketone
N-[2-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-4-oxo-3-quinazolinyl]benzamide[no description available]low00aromatic ketone
3-methyl-2-methylene-1,5-diphenylpentane-1,5-dione[no description available]low00aromatic ketone
2-[1-(2-methylphenyl)-3-oxo-3-thiophen-2-ylpropyl]propanedinitrile[no description available]low00aromatic ketone
(4-chlorophenyl)-(7-methyl-3-imidazo[1,2-a]pyridinyl)methanone[no description available]low00aromatic ketone
2-[(4-hydroxy-3-nitrophenyl)sulfonylamino]benzoic acid [2-(4-methoxyphenyl)-2-oxoethyl] ester[no description available]low00aromatic ketone
4-benzoyl-2-heptyl-5-methyl-4H-pyrazol-3-one[no description available]low00aromatic ketone
(4-benzoyl-1-methyl-3-pyrrolidinyl)-phenylmethanone[no description available]low00aromatic ketone
6-benzoyl-2-phenyl-5-(trifluoromethyl)-3-pyridazinone[no description available]low00aromatic ketone
LY-310762[no description available]low00aromatic ketone;
monofluorobenzenes;
oxindoles;
piperidines;
tertiary amino compound		receptor modulator;
serotonergic antagonist
1-(4-methylphenyl)-2-[(1-phenyl-2-imidazolyl)thio]ethanone[no description available]low00aromatic ketone
gr 103691[no description available]low00aromatic ketone
4-(1,3-dioxo-2-benzo[de]isoquinolinyl)butanoic acid [2-(2-acetylanilino)-2-oxoethyl] ester[no description available]low00aromatic ketone
2-chloro-N-(2,6-dimethylphenyl)-3-oxo-3-phenylpropanamide[no description available]low00aromatic ketone
1-(4-chlorophenyl)-2-[[3-(3-methylphenyl)-1,2,4-thiadiazol-5-yl]thio]ethanone[no description available]low00aromatic ketone
N-(3-acetylphenyl)-2-[[6-chloro-3-(2-hydroxypropyl)-4-methyl-2-oxo-1-benzopyran-7-yl]oxy]acetamide[no description available]low00aromatic ketone
4-[4-(4-acetylphenyl)-1-piperazinyl]-N-[3-(dimethylamino)propyl]-3-nitrobenzenesulfonamide[no description available]low00aromatic ketone
2-chloro-1-[1-(3-isoxazolyl)-2,5-dimethyl-3-pyrrolyl]ethanone[no description available]low00aromatic ketone
5-[(5-bromo-2-hydroxyphenyl)-oxomethyl]-1-cyclohexyl-2-oxo-3-pyridinecarbonitrile[no description available]low00aromatic ketone
2-[(5-ethyl-2-thiophenyl)-oxomethyl]benzoic acid[no description available]low00aromatic ketone
3-[4-(4-morpholinylsulfonyl)phenyl]propanoic acid [2-(4-acetylanilino)-2-oxoethyl] ester[no description available]low00aromatic ketone
rottlerin[no description available]low00aromatic ketone;
benzenetriol;
chromenol;
enone;
methyl ketone		anti-allergic agent;
antihypertensive agent;
antineoplastic agent;
apoptosis inducer;
K-ATP channel agonist;
metabolite
isoegomaketone[no description available]low00aromatic ketone
palbociclib[no description available]low00aminopyridine;
aromatic ketone;
cyclopentanes;
piperidines;
pyridopyrimidine;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
radicinin[no description available]low00aromatic ketone
oxyfedrine[no description available]low00aromatic ketone
3-(dimethylamino)-1-(5-methyl-3-phenyl-4-isoxazolyl)-2-propen-1-one[no description available]low00aromatic ketone
2-[[5,6-bis(2-furanyl)-1,2,4-triazin-3-yl]thio]-1-(4-methoxyphenyl)ethanone[no description available]low00aromatic ketone
buflomedil hydrochloride[no description available]low00aromatic ketone
ciproxifan[no description available]low00aromatic ketone
4'-methyl-alpha-pyrrolidinopropiophenone[no description available]low00aromatic ketone
l-165041[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-[[3-(2-pyridinyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]thio]acetamide[no description available]low00aromatic ketone
N-[4-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]phenyl]acetamide[no description available]low00aromatic ketone
6-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-3,4-dihydro-1H-quinolin-2-one[no description available]low00aromatic ketone
2-(2-benzoyl-1-pyrrolyl)-N-methyl-N-(phenylmethyl)acetamide[no description available]low00aromatic ketone
ic 86621[no description available]low00aromatic ketone
scio-469[no description available]low00aromatic amide;
aromatic ketone;
chloroindole;
dicarboxylic acid diamide;
indolecarboxamide;
monofluorobenzenes;
N-acylpiperazine;
N-alkylpiperazine		antineoplastic agent;
apoptosis inducer;
EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
am 694[no description available]low00aromatic ketone;
indoles;
organofluorine compound;
organoiodine compound;
synthetic cannabinoid		cannabinoid receptor agonist
fonsecinone a[no description available]low00aromatic ether;
aromatic ketone;
biaryl;
cyclic ketone;
naphtho-gamma-pyrone;
polyphenol		antibacterial agent;
Aspergillus metabolite
e 5555[no description available]low00aromatic ketone
cytosporone b[no description available]low00aromatic ketone
benzobicyclon[no description available]low00aromatic ketone;
carbobicyclic compound;
cyclic ketone;
monochlorobenzenes;
organic sulfide;
sulfone
tembotrione[no description available]low00aromatic ketone;
beta-triketone;
cyclic ketone;
ether;
monochlorobenzenes;
organofluorine compound;
sulfone		agrochemical;
carotenoid biosynthesis inhibitor;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide
y134 compound[no description available]low00aromatic ketone
N-[2-(3,4-dimethoxyphenyl)ethyl]-4-(4-ethoxyphenyl)-2,4-dioxobutanamide[no description available]low00aromatic ketone
[9-(benzenesulfonyl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinolin-8-yl]-(4-methylphenyl)methanone[no description available]low00aromatic ketone;
quinolines
alpha(-(cyclopropylcarbonyl)-2-(methyvlsulfonyl)-beta-oxo-4-(trifluromethyl)benzenepropanenitrile)[no description available]low00(trifluoromethyl)benzenes;
aromatic ketone;
beta-diketone;
cyclopropanes;
nitrile;
sulfone		agrochemical;
EC 1.13.11.27 (4-hydroxyphenylpyruvate dioxygenase) inhibitor;
herbicide
aflatoxin m1[no description available]low00aflatoxin;
aromatic ether;
aromatic ketone;
tertiary alcohol		Aspergillus metabolite;
human xenobiotic metabolite;
mammalian metabolite
acetic acid [4-[[(3aS,4R,9aS,9bR)-2-(2-naphthalenyl)-1,3-dioxo-3a,4,9a,9b-tetrahydropyrrolo[1,2]pyrrolo[3,5-b]pyridazin-4-yl]-oxomethyl]phenyl] ester[no description available]low00aromatic ketone
(3R,3aR,7aR)-3-[4-(4-acetylphenyl)-2-fluorophenyl]-7a-methyl-2-(phenylmethyl)-3,3a,6,7-tetrahydroisoindol-1-one[no description available]low00aromatic ketone
(3-propan-2-yloxyphenyl)-[1-[(1-propan-2-yl-4-pyrazolyl)methyl]-3-piperidinyl]methanone[no description available]low00aromatic ketone
[2-(methylthio)phenyl]-[1-[oxo(4-thiadiazolyl)methyl]-3-piperidinyl]methanone[no description available]low00aromatic ketone
2-(3,5-dimethyl-1-pyrazolyl)-1-[3-[oxo-(3-propan-2-yloxyphenyl)methyl]-1-piperidinyl]ethanone[no description available]low00aromatic ketone
[1-[(5-methyl-1-propyl-4-pyrazolyl)methyl]-3-piperidinyl]-(3-propan-2-yloxyphenyl)methanone[no description available]low00aromatic ketone
[1-[[1-(5-chloro-2-pyridinyl)-2-pyrrolyl]methyl]-3-piperidinyl]-(2,4-dimethoxyphenyl)methanone[no description available]low00aromatic ketone
2-(2-acetyl-3,5-dihydroxyphenyl)acetic acid[no description available]low00aromatic ketone
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone[no description available]low00aromatic ketone;
catechols;
thiocyanates
(3R,3aS,7R,7aS)-3-[3-(4-acetylphenyl)-4-fluorophenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one[no description available]low00aromatic ketone
N-(3-acetylphenyl)-5-(3-methyl-5-isoxazolyl)-2-thiophenesulfonamide[no description available]low00aromatic ketone
5-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-1,3-dihydroindol-2-one[no description available]low00aromatic ketone
plx 4720[no description available]low00aromatic ketone;
difluorobenzene;
organochlorine compound;
pyrrolopyridine;
sulfonamide		antineoplastic agent;
B-Raf inhibitor
lcl161[no description available]low001,3-thiazoles;
aromatic ketone;
L-alanine derivative;
monofluorobenzenes;
N-acylpyrrolidine		antineoplastic agent;
apoptosis inducer
a-922500[no description available]low00aromatic ketone
marinopyrrole a[no description available]low00aromatic ketone;
organochlorine compound;
phenols;
pyrroles		antibacterial agent;
antimicrobial agent;
antineoplastic agent;
bacterial metabolite;
marine metabolite
plx4032[no description available]low00aromatic ketone;
difluorobenzene;
monochlorobenzenes;
pyrrolopyridine;
sulfonamide		antineoplastic agent;
B-Raf inhibitor
1-[2-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]phenyl]ethanone[no description available]low00aromatic ketone;
thienopyrimidine
cblc137[no description available]low00aromatic ketone;
carbazoles;
methyl ketone;
secondary amino compound;
tertiary amino compound		antineoplastic agent;
apoptosis inducer;
NF-kappaB inhibitor;
p53 activator
myrtucommulone a[no description available]low00aromatic ketone
(3,4-dimethoxyphenyl)-[1-(2-phenylethyl)-3-piperidinyl]methanone[no description available]low00aromatic ketone
[1-(cyclohexylmethyl)-3-piperidinyl]-(3,4-dimethoxyphenyl)methanone[no description available]low00aromatic ketone
yk 4-279[no description available]low00aromatic ketone
1-[3-[4-[(1-methyl-5-tetrazolyl)thio]-5-thieno[2,3-d]pyrimidinyl]phenyl]ethanone[no description available]low00aromatic ketone;
thienopyrimidine
5-[[4-(4-acetylphenyl)-1-piperazinyl]sulfonyl]-3,3-dichloro-1H-indol-2-one[no description available]low00aromatic ketone
mephedrone[no description available]low00amphetamines;
aromatic ketone;
secondary amino compound		environmental contaminant;
xenobiotic
alectinib[no description available]low00aromatic ketone;
morpholines;
nitrile;
organic heterotetracyclic compound;
piperidines		antineoplastic agent;
EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
4-methylethcathinone[no description available]low00aromatic ketone
3,4-dimethylmethcathinone[no description available]low00aromatic ketone
pogostone[no description available]low00aromatic ketone
ilicicolin h[no description available]low00aromatic ketone;
carbobicyclic compound;
ilicicolin;
monohydroxypyridine;
octahydronaphthalenes;
phenols;
pyridone		antimicrobial agent;
mitochondrial respiratory-chain inhibitor
[4-amino-2-[2-methoxy-4-(4-methyl-1-piperazinyl)anilino]-5-thiazolyl]-(2,6-dichlorophenyl)methanone[no description available]low00aromatic ketone
biliatresone[no description available]low00aromatic ether;
aromatic ketone;
benzodioxoles;
enone;
phenols		plant metabolite;
toxin
myxopyronin b[no description available]low00aromatic ketone
N-(4-acetylphenyl)-2-[(4-oxo-1H-quinazolin-2-yl)thio]butanamide[no description available]low00aromatic ketone
6-amino-2-[[2-(3,4-dimethylphenyl)-2-oxoethyl]thio]-1H-pyrimidin-4-one[no description available]low00aromatic ketone
3-(4-oxo-1H-quinazolin-2-yl)propanoic acid [1-(4-bromophenyl)-1-oxopropan-2-yl] ester[no description available]low00aromatic ketone
nbi 31772[no description available]low00aromatic ketone;
benzenediols;
hydroxy monocarboxylic acid;
isoquinolines;
tetrol		insulin-like growth factor-binding protein inhibitor
ConditionIndicatedRelationship StrengthStudiesTrials
Encephalitis, Polio0low10
Epidemic Acute Poliomyelitis0low10
Infantile Paralysis0low10
Inflammation0low10
Innate Inflammatory Response0low10
Polio0low10
Polio Encephalitis0low10
Poliomyelitis0low10
Poliomyelitis Infection0low10
Poliomyelitis, Acute0low10
Poliomyelitis, Nonpoliovirus0low10
Poliomyelitis, Preparalytic0low10